The “New” Head and Neck Cancer Patient—Young, Nonsmoker, Nondrinker, and HPV Positive: Evaluation
Identifieur interne : 000B98 ( Main/Exploration ); précédent : 000B97; suivant : 000B99The “New” Head and Neck Cancer Patient—Young, Nonsmoker, Nondrinker, and HPV Positive: Evaluation
Auteurs : Daniel G. Deschler [États-Unis] ; Jeremy D. Richmon [États-Unis] ; Samir S. Khariwala [États-Unis] ; Robert L. Ferris [États-Unis] ; Marilene B. Wang [États-Unis]Source :
- Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [ 0194-5998 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Carcinome épidermoïde (), Carcinome épidermoïde (virologie), Carcinome épidermoïde (épidémiologie), Consommation de boisson, Facteurs de l'âge, Femelle, Humains, Infections à papillomavirus (), Infections à papillomavirus (diagnostic), Infections à papillomavirus (épidémiologie), Mâle, Prévalence, Tabagisme, Tumeurs de l'oropharynx (), Tumeurs de l'oropharynx (virologie), Tumeurs de l'oropharynx (épidémiologie), Tumeurs de la tête et du cou (virologie), Tumeurs de la tête et du cou (épidémiologie), États-Unis d'Amérique (épidémiologie), Évaluation des risques.
- MESH :
- diagnostic : Infections à papillomavirus.
- virologie : Carcinome épidermoïde, Tumeurs de l'oropharynx, Tumeurs de la tête et du cou.
- épidémiologie : Carcinome épidermoïde, Infections à papillomavirus, Tumeurs de l'oropharynx, Tumeurs de la tête et du cou, États-Unis d'Amérique.
- Adulte, Carcinome épidermoïde, Consommation de boisson, Facteurs de l'âge, Femelle, Humains, Infections à papillomavirus, Mâle, Prévalence, Tabagisme, Tumeurs de l'oropharynx, Évaluation des risques.
- Wicri :
- geographic : États-Unis.
English descriptors
- KwdEn :
- Adult, Age Factors, Carcinoma, Squamous Cell (epidemiology), Carcinoma, Squamous Cell (therapy), Carcinoma, Squamous Cell (virology), Drinking, Female, Head and Neck Neoplasms (epidemiology), Head and Neck Neoplasms (virology), Humans, Male, Oropharyngeal Neoplasms (epidemiology), Oropharyngeal Neoplasms (therapy), Oropharyngeal Neoplasms (virology), Papillomavirus Infections (diagnosis), Papillomavirus Infections (epidemiology), Papillomavirus Infections (therapy), Prevalence, Risk Assessment, Smoking, United States (epidemiology).
- MESH :
- geographic , epidemiology : United States.
- diagnosis : Papillomavirus Infections.
- epidemiology : Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Papillomavirus Infections.
- therapy : Carcinoma, Squamous Cell, Oropharyngeal Neoplasms, Papillomavirus Infections.
- virology : Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms.
- Adult, Age Factors, Drinking, Female, Humans, Male, Prevalence, Risk Assessment, Smoking.
Abstract
The near epidemic rise of the incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OPSCC) presents the practitioner with a “new” head and neck cancer patient, vastly different from those with the traditional risk factors who formed the basis of most practitioners’ training experience. Accordingly, a thorough and disease-specific evaluation process is necessitated. This article will review the evaluation of the HPV-related cancer patient, including a review of the HPV-positive oropharyngeal cancer epidemic from the surgeon’s perspective, evaluation of the primary lesion, evaluation of the neck mass, and role of imaging, to provide a framework for addressing the challenging questions patients may ask.
Available peer-reviewed literature and practice guidelines.
Assessment of selected specific topics by authors solicited from the Head and Neck Surgery and Oncology Committee of the American Academy of Otolaryngology—Head and Neck Surgery Foundation and the American Head and Neck Society.
The dramatic rise in OPSSC related to HPV is characterized by a “new” cancer patient who is younger and lacks traditional risk factors. Today’s caregiver must be prepared to appropriately evaluate, counsel, and treat these patients with HPV-positive disease with the expectation that traditional treatment algorithms will evolve to maintain or improve current excellent cure rates while lessening treatment related side effects.
Url:
DOI: 10.1177/0194599814538605
PubMed: 24925311
PubMed Central: 4894657
Affiliations:
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Le document en format XML
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Factors</term><term>Drinking</term><term>Female</term><term>Humans</term><term>Male</term><term>Prevalence</term><term>Risk Assessment</term><term>Smoking</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Carcinome épidermoïde</term><term>Consommation de boisson</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Humains</term><term>Infections à papillomavirus</term><term>Mâle</term><term>Prévalence</term><term>Tabagisme</term><term>Tumeurs de l'oropharynx</term><term>Évaluation des risques</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>États-Unis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">The near epidemic rise of the incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OPSCC) presents the practitioner with a “new” head and neck cancer patient, vastly different from those with the traditional risk factors who formed the basis of most practitioners’ training experience. Accordingly, a thorough and disease-specific evaluation process is necessitated. This article will review the evaluation of the HPV-related cancer patient, including a review of the HPV-positive oropharyngeal cancer epidemic from the surgeon’s perspective, evaluation of the primary lesion, evaluation of the neck mass, and role of imaging, to provide a framework for addressing the challenging questions patients may ask.</p></sec><sec id="S2"><title>Data Sources</title><p id="P2">Available peer-reviewed literature and practice guidelines.</p></sec><sec id="S3"><title>Review Methods</title><p id="P3">Assessment of selected specific topics by authors solicited from the Head and Neck Surgery and Oncology Committee of the American Academy of Otolaryngology—Head and Neck Surgery Foundation and the American Head and Neck Society.</p></sec><sec id="S4"><title>Conclusions and Implications for Practice</title><p id="P4">The dramatic rise in OPSSC related to HPV is characterized by a “new” cancer patient who is younger and lacks traditional risk factors. Today’s caregiver must be prepared to appropriately evaluate, counsel, and treat these patients with HPV-positive disease with the expectation that traditional treatment algorithms will evolve to maintain or improve current excellent cure rates while lessening treatment related side effects.</p></sec></div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Maryland</li><li>Massachusetts</li><li>Minnesota</li><li>Pennsylvanie</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Deschler, Daniel G" sort="Deschler, Daniel G" uniqKey="Deschler D" first="Daniel G." last="Deschler">Daniel G. Deschler</name></region><name sortKey="Ferris, Robert L" sort="Ferris, Robert L" uniqKey="Ferris R" first="Robert L." last="Ferris">Robert L. Ferris</name><name sortKey="Khariwala, Samir S" sort="Khariwala, Samir S" uniqKey="Khariwala S" first="Samir S." last="Khariwala">Samir S. Khariwala</name><name sortKey="Richmon, Jeremy D" sort="Richmon, Jeremy D" uniqKey="Richmon J" first="Jeremy D." last="Richmon">Jeremy D. Richmon</name><name sortKey="Wang, Marilene B" sort="Wang, Marilene B" uniqKey="Wang M" first="Marilene B." last="Wang">Marilene B. Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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